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. 2020 Nov 25;7:601206. doi: 10.3389/fmolb.2020.601206

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Copyright © 2020 Wu, Zhang, Chen, Tan, He and Peng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CXCR family genes expression in patients with different grades. (A–G) A significant correlation was found between the expression of CXCR family genes and pathological grade. The mRNA expression of CXCR7 was the highest in grade 3 (G), while the highest mRNA expression of CXCR3/4/5/6 was found in grade 4 (C–F). The highest mRNA expression of CXCR1/2 was detected in grade 1, and the mRNA expression of CXCR1/2 tended to decrease as grade increased (A,B). *p < 0.05, **p < 0.01, ***p < 0.001.