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. 2020 Nov 25;7:601206. doi: 10.3389/fmolb.2020.601206

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Copyright © 2020 Wu, Zhang, Chen, Tan, He and Peng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Survival curves showing the overall survival (OS) times of patients with ccRCC (Kaplan–Meier Plotter). (A-G) Kaplan–Meier (KM) survival curves of CXCR family members. Among the seven CXCR family members, high mRNA expression of CXCR3 (C), CXCR4 (D), CXCR5 (E), CXCR6 (F), and CXCRs (H) were associated with worse OS in ccRCC patients. High CXCR2 (B) were correlated with longer OS time. CXCR1 (A) and CXCR7 (G) showed no significant difference.