Venn diagram showing genetic factors associated with non-alcoholic fatty liver disease and alcoholic liver disease. ADH, alcohol dehydrogenase; ALDH, Aldehyde dehydrogenases; Cyclin-dependent kinase inhibitor 1A, CTLA4: cytotoxic T-lymphocyte associated protein 4, ENPP1, ectoenzyme nucleotide pyrophosphate phosphodiesterase 1; FADS1, fatty acid desaturase 1; GCKR, glucokinase regulatory protein; GCLC, Glutamate-Cysteine Ligase Catalytic Subunit; HSD17B13, 17-beta hydroxysteroid dehydrogenase 13; KLF6, Kruppel-like factor; LPIN1, Lipin 1; MBOAT7, membrane-bound O-acyltransferase domain-containing 7; PNPLA3, patatin-like phospholipase domain-containing protein 3; PPAR alpha, peroxisome proliferator-activated receptor alpha; PEMT, phosphatidylethanolamine N-methyltransferase; PXR, pregnane X receptor; SLC2A1, solute carrier family 2 member 1; SOD2, superoxide dismutase 2; TM6SF2, transmembrane 6 superfamily 2; TNF, tumor necrosis factor.