Table 4. Univariate and multivariate regression analysis of risk factors for postoperative Clavien IV complications and 30 days mortality.

Risk factors	Univariate analysis						Multivariate analysis
	Clavien IV			Mortality			Clavien IV			Mortality
	uOR (95% CI)	P value		uOR (95% CI)	P value		aOR (95% CI)	P value		aOR (95% CI)	P value
Frailty groups
No frailty	ref			ref			ref			ref
Low frailty	1.73 (1.37–2.19)	<0.001		2.99 (1.89–4.77)	<0.001		1.51 (1.18–1.94)	0.001		1.94 (1.18–3.19)	0.009
Intermediate frailty	2.89 (2.26–3.69)	<0.001		5.18 (3.24–8.28)	<0.001		2.4 (1.84–3.13)	<0.001		3.01 (1.79–5.05)	<0.001
Frail	5.1 (3.94–6.59)	<0.001		9.98 (6.24–15.97)	<0.001		3.88 (2.91–5.16)	<0.001		5.12 (3.03–8.65)	<0.001
Age ≥65	2.05 (1.72–2.43)	<0.001		4.615 (3.26–6.53)	<0.001		1.43 (1.19–1.75)	<0.001		3.08 (2.09–4.53)	<0.001
Gender, male	1.4 (1.18–1.65)	<0.001		1.24 (0.95–1.63)	0.116		1.2 (1.01–1.44)	0.042		–	–
BMI ≥30	1.07 (0.88–1.29)	0.49		0.69 (0.49–0.97)	0.031		–			0.87 (0.61–1.25)	0.451
Weight loss >10%	1.26 (1.01–1.58)	0.04		1.76 (1.27–2.45)	0.001		1.32 (1.04–1.68)	0.022		2.03 (1.41–2.93)	<0.001
Chemotherapy	0.77 (0.49–1.21)	0.26		1.99 (1.19–3.33)	0.008		–			2.38 (1.38–4.1)	0.002
Steroid use	2.8 (1.95–4.03)	<0.001		2.84 (1.66–4.84)	<0.001		2.52 (1.72–3.71)	<0.001		2.30 (1.28–4.13)	0.005
HCT <30	2.11 (1.74–2.57)	<0.001		2.29 (1.69–3.1)	<0.001		1.93 (1.57–2.37)	<0.001		1.92 (1.37–2.68)	<0.001
Type of gastrectomy
Distal gastrectomy	ref			ref			ref			–	–
Total gastrectomy	1.26 (1.05–1.53)	0.015		0.694 (0.69–1.32)	0.796		1.42 (1.16–1.73)	<0.001		–	–
Gastrectomy with pouch formation	1.21 (0.79–184)	0.39		0.84 (0.39–1.82)	0.664		1.37 (0.87–2.15)	0.171		–	–

aOR, adjusted odds ratios; uOR, unadjusted odds ratios.