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. Author manuscript; available in PMC: 2020 Dec 9.
Published in final edited form as: ACS Chem Biol. 2020 Feb 17;15(3):640–645. doi: 10.1021/acschembio.9b01038

Figure 2.

Figure 2.

pY39 has a Bidirectional Effect on αS Aggregation. Left: Addition of αS-pY39 (orange bars) or αS-E39 (teal bars) increases aggregation rates at low percentages, but slows aggregation at high percentages. Right: The amount of total monomer incorporated into fibrils is changed more by αS-E39 than by αS-pY39. Experimental details and primary data given in SI.