Table 2.
Correlations between plasma extracellular vesicle (EV) neurofilament light chain (NfL) level and clinical manifestations in patients with Parkinson’s disease. Statistical analysis was conducted by Spearman’s rank correlation.
| Age (years) | Disease duration (years) | UPDRS-III | Akinetic rigidity score | Tremor score | MMSE | MoCA | ||
|---|---|---|---|---|---|---|---|---|
| EV NfL level | Correlation coefficient | 0.047 | 0.202 | 0.16 | 0.183 | 0.075 | 0.056 | 0.037 |
| p value | 0.62 | 0.04* | 0.09 | 0.05 | 0.42 | 0.56 | 0.70 |
*
p < 0.05.
MMSE, Mini-Mental State Examination; MoCA, Montreal Cognitive Assessment; UPDRS, Unified Parkinson’s Disease Rating Scale.