Figure 2.

Vinp attenuates Dex-induced osteoblasts apoptosis via activating the Akt pathway. Osteoblasts were treated with various concentrations of Vinp (5 and 10 μM) and with or without stimulated with Dex (10 μM) for 24 h or 2 h. (A) Apoptotic osteoblasts detection by flow cytometry. Quantitative analyze of Apoptosis rate was conducted (B). The protein expressions of Akt and p-Akt in osteoblasts were visualized by western blotting (C), and quantified in (D). The data in the figures represent the averages ± S.D. ^##P < 0.01 compared with Control group. **P < 0.01 compared with Dex group. n = 3.