Table 3.

Statistical power and sensitivity for regulation success and clinical measures excluding the pilot, proof-of-principle, and feasibility studies. The mean and median values of statistical power and sensitivity are presented, but only for studies that were not labeled as pilot, feasibility, or proof-of-principle. Power is estimated (in percentage) for small, medium, and large effects (based on Cohen’s d of 0.2, 0.5, and 0.8, respectively). Sensitivity, or estimation of detected effect size (based on Cohen’s d) with a certain power, is calculated for the power of 80 and 95%. Power and sensitivity calculations for regulation success include studies reporting a group analysis; clinical measures include power and sensitivity estimation for studies performing a group analysis of clinical measures. For additional information, including individual values for each study, see the Supplementary materials.

			Power			Sensitivity (in Cohen’s d)
		N	d = 0.2	d = 0.5	d = 0.8	Power = 80%	Power = 95%
Regulation success	Mean	29.88	0.24	0.61	0.76	0.77	>0.99
	Median	22.50	0.15	0.67	0.98	0.58	0.73
Clinical measures	Mean	26.73	0.31	0.73	0.85	0.58	0.74
	Median	27	0.30	0.98	>0.99	0.36	0.46