Figure 3.

Insulin-Dependent Mitochondrial Respiration Is Cell-type Specific

(A–C) OCRs were measured by Mito Stress Test in mesendoderm progenitors (A), ectoderm progenitors (B), and fibroblasts (C) after 1 h of pre-incubation with or without insulin.

(D) OCR of fibroblasts measured with different substrate (glucose-Glc, glutamine-Gln, pyruvate-Pyr) combinations.

(E) Spare respiratory capacity calculated from (D).

(F) Spare respiratory capacity calculated from (D) and Figure 2A.

Data are presented as means ± SD.