TABLE 3.
Univariable and multivariable analysis for suicide of leukemia patients
| Variables | Univariable analysis | Multivariable analysis | ||
|---|---|---|---|---|
| HR(95%CI) | p | HR(95%CI) | p | |
| Year of diagnosis | ||||
| 1975–1984 | Reference | Reference | ||
| 1985–1994 | 0.89 (0.57–1.40) | 0.616 | 0.87 (0.50–1.51) | 0.619 |
| 1995–2004 | 0.72 (0.46–1.14) | 0.165 | 0.53 (0.21–1.38) | 0.192 |
| 2005–2017 | 0.99 (0.64–1.53) | 0.977 | 0.70 (0.25–1.97) | 0.493 |
| Sex | ||||
| Female | Reference | Reference | ||
| Male | 4.41 (2.93–6.63) | <0.001*** | 4.73 (3.13–7.11) | <0.001*** |
| Age at diagnosis | ||||
| ≤39 | Reference | Reference | ||
| 40–49 | 1.41 (0.71–2.79) | 0.33 | 1.35 (0.68–2.70) | 0.391 |
| 50–59 | 1.32 (0.73–2.38) | 0.356 | 1.37 (0.75–2.50) | 0.303 |
| 60–69 | 2.60 (1.60–4.23) | <0.001*** | 2.89 (1.73–4.81) | <0.001*** |
| 70–79 | 2.84 (1.72–4.68) | <0.001*** | 3.36 (1.98–5.69) | <0.001*** |
| ≥80 | 2.94 (1.65–5.21) | <0.001*** | 3.85 (2.10–7.04) | <0.001*** |
| Race | ||||
| Black | Reference | Reference | ||
| White | 6.80 (1.69–27.40) | 0.007** | 5.90 (1.46–23.84) | 0.013* |
| Other | 2.43 (0.45–13.28) | 0.305 | 2.46 (0.45–13.48) | 0.298 |
| Unknown | — | — | — | — |
| Race Latino | ||||
| Latino | Reference | Reference | ||
| Non‐Latino | 1.12 (0.62–2.01) | 0.702 | 1.22 (0.65–2.28) | 0.530 |
| Race Hispanic | ||||
| Hispanic | Reference | Reference | ||
| Non‐Hispanic White | 1.00 (0.56–1.79) | 0.998 | 0.80 (0.43–1.48)） | 0.993 |
| Non‐Hispanic Black | 0.15 (0.03–0.66) | 0.013* | 0.06（0.01–0.62） | 0.019* |
| Non‐Hispanic Asian | 0.31 (0.09–1.08) | 0.067 | 0.23（0.13–0.85） | 0.032* |
| Non‐Hispanic American Indian Native | — | — | — | — |
| Non‐Hispanic Unknown Race | — | — | — | — |
| Type of leukemia | ||||
| Lymphoid leukemia | Reference | Reference | ||
| Acute myeloid leukemia | 1.59 (1.09–2.33) | 0.016* | 2.27 (1.53–3.37) | <0.001*** |
| Chronic myeloproliferative diseases | 1.24 (0.78–1.98) | 0.366 | 1.60 (0.99–2.56) | 0.052 |
| Myelodysplastic syndrome and other myeloproliferative | 1.32 (0.42–4.12) | 0.634 | 1.13 (0.35–3.59) | 0.838 |
| Unspecified and other specified leukemia | 2.72 (1.55–4.75) | <0.001*** | 3.21 (1.82–5.66) | <0.001*** |
| Surgery performed | ||||
| Yes | 1.05 (0.78–1.42) | 0.748 | 1.43 (0.68–3.02) | 0.339 |
| No | Reference | Reference | ||
| Primary diseases | ||||
| Yes | 1.03 (0.73–1.44) | 0.88 | 1.34 (0.95–1.90) | 0.098 |
| No | Reference | Reference | ||
| Chemotherapy | ||||
| Yes | 0.862 (0.65–1.15) | 0.312 | 0.88 (0.66–1.17) | 0.370 |
| No | Reference | Reference | ||
| Household income | ||||
| <$50,000 | Reference | Reference | ||
| $55,000–$74,999 | 1.00 (0.69–1.45) | 0.996 | 1.27 (0.83–1.95) | 0.279 |
| >$75,000 | 1.19 (0.66–2.17) | 0.564 | 1.04 (0.54–2.00) | 0.904 |
| Unknown | 1.12 (1.77–1.63) | 0.548 | 0.51 (0.11–2.46) | 0.402 |
| Living area a | ||||
| Large city | Reference | Reference | ||
| Medium city | 1.06 (0.66–1.69) | 0.821 | 1.03 (0.63–1.68) | 0.903 |
| Small city | 2.10 (1.23–3.60) | 0.007** | 2.16 (1.18–3.95) | 0.013* |
| Suburbs | 1.59 (0.88–2.90) | 0.127 | 1.48 (0.78–2.83) | 0.234 |
| Rural | 1.29 (0.66–2.52) | 0.455 | 1.23 (0.58–2.65) | 0.592 |
| Unknown | 1.29 (0.77–1.87) | 0.174 | 2.51 (0.57–10.96) | 0.223 |
a
Large city, Counties in metropolitan areas of 1 million pop; Medium city, Counties in metropolitan areas of 250,000 to 1 million pop; Small city, Counties in metropolitan areas of lt 250 thousand pop; Suburbs, Nonmetropolitan counties adjacent to a metropolitan area; Rural, Nonmetropolitan counties not adjacent to a metropolitan area; Unknown, Unknown/missing/no match/Not 1990–2017.
*
p < 0.05.
**
p < 0.01.
***
p < 0.001.