Table 1.
Patient demographics and baseline characteristics (ITT population).
| Total (N=61) | |
|---|---|
| Female, n (%) | 29 (47.5) |
| Age (years), mean (SD) | 42.2 (14.5) |
| BMI (kg/m2), mean (SD) | 24.3 (3.9) |
| Smoking status, n (%) | |
| Current | 3 (4.9) |
| Former | 11 (18.0) |
| Never | 47 (77.0) |
| Duration of UC (years), median (IQR) | 3.3 (1.6, 7.2) |
| Time since first symptoms (years), median (IQR) | 3.3 (2.1, 7.2) |
| Course of disease, n (%) | |
| Continuous | 7 (11.5) |
| Recurrent | 54 (88.5) |
| Previous episodes of UCa, n (%) | |
| >1 per month | 2/54 (3.7) |
| 1 every 6 months | 13/54 (24.1) |
| 1 every 6–12 months | 25/54 (46.3) |
| <1 per year | 14/54 (25.9) |
| Duration of current acute episode (months), median (IQR) | 2 (1.2, 3.7) |
| Localisation of disease, n (%) | |
| Proctosigmoiditis | 37 (60.7) |
| Left-sided colitis | 16 (26.2) |
| Subtotal/total colitis | 8 (13.1) |
| Length of lesion above the anus (cm), median (IQR) | 40 (25, 55) |
| Stools per week, mean (SD) | 32.5 (17.1) |
| Bloody stools per week, mean (SD) | 17.6 (14.9) |
| CAI, mean (SD) | 7.6 (1.8) |
| Faecal calprotectin (µg/g), median (IQR) | 314 (119.5, 781.5) |
| Concomitant medication, n (%) | 40 (65.6) |
aOnly patients with recurrent UC.
BMI: body mass index; CAI: Clinical Activity Index; IQR: interquartile range; ITT: intention-to-treat; SD: standard deviation; UC: ulcerative colitis.