Table 2. Effect of Vitamin D3 Supplementation During Pregnancy on Language Scores.
| Median (IQR) | Risk ratio P value | |||
|---|---|---|---|---|
| High dose | Standard dose | Unadjusted | Adjusteda | |
| Age 1 y language test | ||||
| Children, No. | 137 | 147 | 284 | 281 |
| Word production | 2 (0-6) | 3 (1-6) | .13 | .16 |
| Girls | 3 (1-7) | 3 (1-6) | .63 | .58 |
| Boys | 1 (0-5) | 4 (1-7) | .11 | .13 |
| Age 2 y language test | ||||
| Children, No. | 199 | 194 | 393 | 390 |
| Word production | 232.0 (113.0-346.0) | 253.0 (149.0-382.5) | .01 | .02 |
| Girls | 274.5 (156.8-383.8) | 307.0 (187.2-412.2) | .12 | .14 |
| Boys | 190.0 (66.0-320.0) | 195.5 (94.8-344.3) | .09 | .14 |
Abbreviation: IQR, interquartile range.
a
Adjusted for maternal preintervention serum vitamin D3 levels, n-3 LPUFA RCT allocation, season of birth, and for overall analyses additionally for sex. Three mothers were missing preintervention serum vitamin D3 results.