Table 3. Effect of Vitamin D3 Supplementation During Pregnancy on the Cognitive Composite Score of the Bayley-III Test.
Outcome | Vitamin D3 dose, mean (SD) | Unadjusted (n = 503) | Adjusted (n = 501)a | |||
---|---|---|---|---|---|---|
High (n = 245) | Standard (n = 258) | Effect, β (95% CI) | P value | Effect, β (95% CI) | P value | |
Cognitive score | 104.7 (9.5) | 104.5 (9.5) | 0.24 (−1.42 to 1.89) | .78 | 0.34 (−1.32 to 1.99) | .70 |
Girls | 105.6 (9.6) | 105.4 (10.3) | 0.15 (−2.35 to 2.64) | .91 | 0.15 (−2.39 to 2.69) | .91 |
Boys | 104.0 (9.3) | 103.5 (8.4) | 0.46 (−1.71 to 2.63) | .68 | 0.79 (−1.40 to 2.98) | .48 |
Adjusted for maternal preintervention serum vitamin D3 levels, n-3 long-chain polyunsaturated fatty acid RCT allocation, season of birth, and for overall analyses additionally for sex. Two mothers were missing preintervention serum vitamin D3 levels.