Table 4. Effect of Vitamin D3 Supplementation During Pregnancy on Outcomes of the Strengths and Difficulties Questionnaire.
| Outcome | Vitamin D3 dose, No. (%) | Unadjusted (n = 496) | Adjusted (n = 493)a | |||
|---|---|---|---|---|---|---|
| High (n = 246) | Standard (n = 250) | OR (95% CI) | P value | OR (95% CI) | P value | |
| Total difficulties score (above vs below median) | ||||||
| All children | 109 (44.3) | 126 (50.4) | 0.78 (0.55-1.11) | .18 | 0.76 (0.53-1.09) | .14 |
| Girls | 48 (19.5) | 61 (24.4) | 0.78 (0.47-1.29) | .33 | 0.73 (0.43-1.23) | .24 |
| Boys | 61 (24.8) | 65 (26.0) | 0.78 (0.47-1.27) | .32 | 0.77 (0.47-1.27) | .30 |
| Impact score (any vs none) | ||||||
| All children | 36 (14.6) | 28 (11.2) | 1.36 (0.80-2.32) | .26 | 1.33 (0.76-2.30) | .30 |
| Girls | 16 (6.5) | 9 (3.6) | 2.12 (0.91-5.20) | .09 | 1.97 (0.83-4.95) | .13 |
| Boys | 20 (8.1) | 19 (7.6) | 0.99 (0.50-1.96) | .97 | 0.97 (0.48-1.99) | .93 |
Abbreviation: OR, odds ratio.
a
Adjusted for maternal preintervention serum vitamin D3 levels, n-3 long-chain polyunsaturated fatty acid RCT allocation, season of birth, and for overall analyses additionally for sex. Three mothers are missing preintervention serum vitamin D3 levels.