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. 2020 Dec 7;4(23):6023–6033. doi: 10.1182/bloodadvances.2020002711

Table 1.

Univariate CSH analysis of TTP

Protein Cutoff Group n TTP
HR (95% CI) Median TTP (range), mo P
Cereblon 0.045 H 142 0.33 (0.15-0.75) NR (55-NR) .008
L 10 36 (8-NR)
Aiolos 0.351 H 43 1.74 (1.02-2.98) 51 (31-NR) .044
L 109 NR (55-NR)
Ikaros 4.647 H 24 2.05 (1.12-3.74) 42 (26-NR) .020
L 128 NR (55-NR)
AGO2 3.510 H 12 2.60 (1.32-5.14) 42 (25-52) .006
L 156 NR (59-NR)
IRF4 0.539 H 113 0.57 (0.34-0.97) NR (55-NR) .039
L 41 49 (36-NR)
PSMA3 3.985 H 17 1.78 (0.90-3.53) 48 (55-NR) .096
L 141 NR (54.87-NR)
PSME1 0.981 H 107 1.48 (0.81-2.69) 55 (51-NR) .2
L 45 NR (51-NR)
PSMD1 3.458 H 10 3.43 (1.67-7.02) 40 (8-51) <.001
L 148 NR (59-NR)
PSMD4 0.507 H 34 1.86 (1.08-3.21) 48 (35-NR) .026
L 124 NR (59-NR)
PSMD10 0.548 H 115 2.46 (1.17-5.19) 53 (48-NR) .018
L 37 NR (55-NR)
GCR 0.655 H 139 2.96 (0.72-12.12) 59 (51-NR) .131
L 13 NR (NR-NR)
XPO1 2.453 H 91 1.47 (0.86-2.52) 53 (48-NR) .156
L 63 NR (59-NR)

Bold indicates statistically significant P values (P < .05).

CI, confidence interval; NR, not reached.