Table 2.

Stratified Vaccine Effectiveness and 95% Confidence Intervals for RV5 and RV1, 2012–2013

Stratum	RV5		RV1
	Cases/Controls	VE (95% CI)	Cases/Controls	VE (95% CI)
Dose Number
Dose 1	223/635	68% (45%–82%)	64/240	96% (67%–99%)
Dose 2	239/832	78% (66%–85%)	99/735	80% (68%–88%)
Dose 3	354/2117	80% (74%–84%)	NA	NA
Season
2012	67/916	76% (58%–86%)	15/298	73% (11%–92%)
2013	287/1201	80% (73%–85%)	84/437	83% (70%–90%)
Clinical Setting
Inpatient	96/433	83% (71%–90%)	27/148	84% (53%–94%)
ED	258/1684	77% (69%–83%)	72/587	79% (63%–87%)
Year of Life
1	32/398	91% (78%–96%)	20/209	82% (52%–93%)
2	73/591	82% (69%–89%)	30/305	86% (68%–94%)
3	78/368	88% (78%–93%)	31/142	80% (51%–92%)
4	50/241	76% (51%–88%)	14/57	58% (−64%–89%)
5	44/208	60% (16%–81%)	Φ	Φ
6–7	77/296	69% (43%–84%)	Φ	Φ
Predominant Genotype
G1, P[8]	11/2117	89% (55%–97%)	Φ	Φ
G2, P[4]	21/2117	87% (65%–95%)	20/735	53% (−26%–82%)
G3, P[8]	58/2117	80% (64%–89%)	24/735	88% (70%–95%)
G12, P[8]	249/2117	78% (71%–84%)	50/735	82% (66%–91%)
Ethnicity
Hispanic	130/909	72% (57%–81%)	21/175	81% (46%–93%)
Non-Hispanic	222/1206	81% (74%–87%)	78/558	80% (65%–88%)

ф = Insufficient RV1 coverage/subjects.

Exact odds ratio (95% CI).

Abbreviations: CI, confidence interval; ED, emergency department; NA, not applicable; VE, vaccine effectiveness.