Table 3.
Inc plasmid classification and associated biological traits
| PBRT group (corresponding Pseudomonas PBRT in parenthesis) | Examplesa | Targets for PCR-based replicon typing (82) | Plasmid copy number (10) | Size range (kb) (10) | Host range (5, 10) | HGT (10) | Additional notes |
|---|---|---|---|---|---|---|---|
| IncP (IncP-1) | RK2 (1α)R751 (1β)pJP4pQK54pKJK5RP1RP4R68R18 | Iterons | 5–7 | 70–275 | Broad | Conjugative | Environmental: found in manure, soils, water treatment plantsExtremely stable |
| IncHI1 | R27 | Low | 75–400 | Broad | Conjugative | HI1A/B multireplicon, frequently also IncFIA/B, occasionally also IncX1 | |
| IncHI2 | R478 | Low | 75–400 | Broad | Conjugative | Usually IncF-compatible | |
| IncFIA | F | Iterons | Low | 45–200 | Enterobacteriaceae | Conjugative | Multireplicon plasmid with combinations of FIA/B, FII, and FrepBMost frequent in human (North and South America) and animal (Asia) sources |
| IncFIB | repA | ||||||
| IncFII | R1NR-1R6-5 | repA2 | |||||
| IncFrepB | RNAI/repA | ||||||
| IncN | N3pCU1R46 | repA | Low | 30–70 | Broad(relative) | Conjugative | Animal-associated environmentsOften colocalized with IncF |
| IncA/C (IncP-3) | RA1, pRMH760 | repA | Low | 18–230 | Narrow | Conjugative | |
| IncL | pK01-34R471pEL60 | repA, repB, repC | Low | 60-90 | Broad | Conjugative | Highly conserved, sharing the majority of their genes.Important role in dissemination of β-lactamases |
| IncR | pKP1780 | repB | 40–160 | Broad | Mobilizable | ||
| IncY | P1pMCR-1-P3 | repA | Low | 90–140 | Prophage | ||
| IncQ (IncP-4) | RSF1010IncP-4R1162R300B | Medium (4–12 copies/cell) | 8–14 | Broad | Mobilizable | Lacks partitioning or plasmid stability system | |
| IncW | R388R7KpSapVX2 | repA | Low | <40 | Broad | ConjugativeSmallest conjugative plasmid; can act as helper for ColE and IncQ | |
| ColE | ColE-like ori | Variable (1–20 copies/cell) | 6–40 | Narrow | Mobilizable | Produce colicins, proteins produced by certain strains of E. coli lethal for related strainsAssociated with the spread of qnrS1, qnrB19 |
a
Partially based on reference 97.