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. 2020 Apr 28;1(6):501–509. doi: 10.34067/KID.0000962019

Figure 1.

Figure 1.

Acute infusion of ascorbic acid differentially improved brachial artery flow-mediated dilation in healthy controls as compared to participants with CKD. Brachial artery flow-mediated dilation (FMD) after an acute infusion of saline (black bars) and ascorbic acid (gray bars) in participants with CKD and healthy controls. Infusions were performed in all control participants (n=17) and n=60 participants with CKD. Ascorbic acid significantly improved brachial artery FMD in control participants (saline, 5.5%±0.8%; ascorbic acid, 6.8%±0.9%) as compared with participants with CKD (saline, 3.5%±0.4%; ascorbic acid, 3.6%±0.4%) (group×condition interaction P=0.04). Values are mean±SEM.