Table 1.

Time interval between cessation or pausing of an immunosuppressive agent and live vaccination (modified from Ref [81])

Medication	Time interval
Corticosteroids Systemic: only short term (<2 weeks) or low dose (<20mg/d of prednisone or equivalent (adult) or <2mg/kg/day (children)) Maintenance physiologic doses (replacement therapy) Non-systemic glucocorticoids (topical or injections) Balsalazide Budenoside (≤ 6mg/day) Mesalazine Olsalazine Sulfasalazine Vedolizumab	No time lag needed
Corticosteroids Systemic and high dose (≥20mg per day of prednisone or equivalent (adult) or ≥2mg/kg/day (children)) and ≥ 2 weeks	1 month
Ciclosporine A Cyclophosphamide Mycophenolate Tacrolimus	3 months
Azathioprine Methotrexate 6-Mercaptopurine 6-Thioguanine	3 months
Adalimumab Certolizumab Golimumab Infliximab Ustekinumab	3 months
Leflunomide	6 months