Table 1. Comparison of baseline characteristics.
| AKI (n = 28) | No AKI (n = 676) | P value | |
|---|---|---|---|
| Age (years) | 74.3 ± 12.1 | 57.0 ± 17.4 | < 0.001 |
| Male patient (%) | 16 (57.1) | 194 (28.7) | 0.001 |
| Hypertension (%) | 22 (78.6) | 204 (30.2) | < 0.001 |
| Diabetes mellitus (%) | 16 (57.1) | 107 (15.8) | < 0.001 |
| White blood cells (x103/μL) | 7.53 ± 4.77 | 5.4 ± 2.0 | 0.023 |
| Neutrophil (%) | 70.2 ± 12.4 | 58.3 ± 13.1 | < 0.001 |
| Lymphocyte (%) | 20.3 ± 10.6 | 31.1 ± 11.6 | < 0.001 |
| Hemoglobin (g/dL) | 11.8 ± 1.9 | 12.6 ± 1.5 | 0.007 |
| Platelet count (x103/μL) | 179.5 ± 85.2 | 233.2 ± 82.2 | 0.001 |
| Sodium (mmol/L) | 138.0 ± 3.6 | 140.1 ± 3.6 | 0.003 |
| Potassium (mmol/L) | 4.4 ± 0.8 | 4.1 ± 0.5 | 0.108 |
| Blood urea nitrogen (mg/dL) | 27.6 ± 21.0 | 14.5 ± 6.3 | 0.003 |
| Creatinine (mg/dL) | 1.6 ± 1.1 | 0.8 ± 0.3 | 0.001 |
| eGFR (ml/min/1.73 m2) | 56.3 ± 30.8 | 93.1 ± 22.7 | < 0.001 |
| eGFR < 60 ml/min/1.73 m2 | 16 (57.1) | 52 (7.7) | < 0.001 |
| Albumin (g/dL) | 3.4 ± 0.5 | 4.2 ± 2.9 | 0.147 |
| C-reactive protein (mg/dL) | 7.9 ± 6.9 | 2.0 ± 4.0 | < 0.001 |
| Creatine kinase (U/L) | 93.7 ± 81.1 | 103.1 ± 291.6 | 0.872 |
| Lactate dehydrogenase (U/L) | 840.6 ± 916.4 | 487.8 ± 181.0 | 0.061 |
| Chest X-ray infiltration (%) | 24 (85.7) | 335 (49.6) | < 0.001 |
| Medication (%) | < 0.001 | ||
| None | 0 (0) | 204 (30.2) | 0.001 |
| Lopinavir/ritonavir | 21 (75.0) | 243 (35.9) | < 0.001 |
| Hydroxychloroquine | 7 (25.0) | 229 (33.9) | 0.330 |
Values are presented as mean ± standard deviation or number (%).
AKI, acute kidney injury; eGFR, estimated glomerular filtration rate.