Table 5. Multivariable Cox proportional hazard model to identify risk factors for in-hospital mortality.
Variables | Univariable | Multivariable | ||||
---|---|---|---|---|---|---|
HR | 95% CI | P value | HR | 95% CI | P value | |
Age ≥ 65 (years) | 11.507 | 3.431–38.597 | < 0.001 | 4.668 | 1.250–17.430 | 0.022 |
Male sex | 3.580 | 1.589–8.066 | 0.002 | 1.062 | 0.356–3.166 | 0.914 |
Hypertension | 6.026 | 2.391–15.186 | < 0.001 | 1.588 | 0.452–5.581 | 0.470 |
Diabetes mellitus | 7.100 | 3.103–16.249 | < 0.001 | 2.470 | 0.900–6.783 | 0.079 |
Neutrophil/lymphocyte ratio | 1.223 | 1.162–1.286 | < 0.001 | 1.167 | 1.078–1.264 | < 0.001 |
Blood urea nitrogen (mg/dL) | 1.075 | 1.055–1.095 | < 0.001 | 0.990 | 0.936–1.048 | 0.738 |
eGFR < 60 (ml/min/1.73 m2) | 10.255 | 4.583–22.949 | < 0.001 | 1.318 | 0.352–4.932 | 0.682 |
Albumin (g/dL) | 0.099 | 0.053–0.183 | < 0.001 | 0.378 | 0.120–1.191 | 0.097 |
C-reactive protein (mg/dL) | 1.141 | 1.098–1.185 | < 0.001 | 0.898 | 0.793–1.016 | 0.089 |
Creatine kinase (U/L) | 1.002 | 1.000–1.003 | 0.006 | 1.002 | 1.001–1.004 | 0.007 |
Lactate dehydrogenase (U/L) | 1.002 | 1.001–1.002 | < 0.001 | 1.001 | 1.000–1.003 | 0.104 |
Severe acute kidney injury | 38.355 | 16.964–86.721 | < 0.001 | 12.199 | 4.235–35.141 | < 0.001 |