FIGURE 4. CD11b⁺c-fms⁺Ly6C^hi population is able to differentiate into OC in vivo.

Pg was injected into the calvaria of C57BL/6 WT mice on day 0. Mice were then injected intravenously with PBS or with CD11b⁺c-fms⁺Ly6C^hi population of Pg-infected mT/mG;c-fms-Cre mice on day 1 and on day 4. Calvarial sections were prepared on day 7 and stained for GFP, TRAP and DAPI. Images are representative of three independent experiments with similar results. Scale bar, 100 μm.