Table 3.
Multiple linear regression analysis of C-peptide with corneal nerve parameters (as dependent variable).
| Models | Characteristics | CNFL | CNFD | CNBD | |||
|---|---|---|---|---|---|---|---|
| β coefficient (95% CI) | P value | β coefficient (95% CI) | P value | β coefficient (95% CI) | P value | ||
| Model 1 | Fasting C-peptide (ng/mL) | 1.160 (0.480 to 1.839) | 0.001 | 1.855 (0.403 to 3.306) | 0.013 | 5.776 (1.802 to 9.750) | 0.005 |
| Model 2 | Fasting C-peptide (ng/mL) | 0.828 (0.010 to 1.647) | 0.047 | 1.227 (-0.573 to 3.027) | 0.180 | 5.297 (0.302 to 10.291) | 0.038 |
| Model 3 | Fasting C-peptide (ng/mL) | 0.716 (-0.117 to 1.549) | 0.091 | 1.158 (-0.685 to 3.000) | 0.216 | 5.104 (-0.005 to 10.212) | 0.050 |
Model 1: unadjusted. Model 2: adjusted for age, gender, BMI, SBP, HbA1c, triglyceride, TC, eGFR, insulin treatment, metformin, alpha glucosidase inhibitor, and other antidiabetic medications. Model 3: adjusted for age, gender, BMI, SBP, HbA1c, triglyceride, TC, eGFR, insulin treatment, metformin, alpha glucosidase inhibitor, other antidiabetic medications, and duration of diabetes.