Fig. 2.

Log hazard ratios of diet and water supplementation in a panel of DGRP genotypes. (A) Dietary reaction norms vary in a genotype-specific manner. (B) Water supplementation, relative to control treatment, rescues desiccation in a diet- and genotype-dependent manner. Hazard ratios represent risk of dying; therefore, higher values indicate shorter lifespans and are relative. Ratios are plotted as coefficients derived from within-line Cox mixed-effects models, with error bars representing 95% confidence intervals (CI). For A, 8% yeast treatment was treated as a reference, and as such, no CIs are available. Rates here are relative to 8% yeast diet, and lines represent this standard; N=25,519 females in total, and 4800–5282 per genotype. For B, hazard rates are relative to the corresponding control for each diet. Horizontal lines represent a water effect size of 0; N=12,737 females in total, and 2396–2629 per genotype.