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. 2020 Dec 1;13(11):dmm043620. doi: 10.1242/dmm.043620

Fig. 8.

Fig. 8.

A. muciniphila treatment restores the type H vessels formation and decreases the gut permeability of DSS-treated mice. (A-D) Representative images of CD31 and Emcn co-immunostaining (A) with quantification of the ratio of total vessels area (TVA), type H vessels area (HVA) and non-type H vessels area (NHA) (L) at 2 WPF. n=3 per group. Scale bar: 500 μm. (E-L) qRT-PCR measurements of colonic mRNA levels of Cldn-2, -3 and -15, Ocln, Jam3, Tnf-α, Il17A and Il10 at 2 and 6 WPF. n=5 per group. (M) LPS levels in serum samples at 2 and 6 WPF. n=5 per group. (N) Serum FITC-dextran levels were measured 4 h after FITC-dextran oral administration at 2 and 6 WPF. n=5 per group. Data are mean±s.d. *P<0.05, **P<0.01, ***P<0.001, unpaired two-tailed Student's t-test.