Table.
References | Age/Sex | Onset of MN at the diagnosis of CCS | Treatments for CCS | Additional treatments for MN | Patient outcome† |
10 | 41/M | 5 years before | Low anterior resection due to rectal adenocarcinoma | None | Remission‡ |
11 | 64/M | 10 months after | Right hemicolectomy due to ascending colon mucinous adenocarcinoma and oral PSL (40 mg/day, tapered later) | Reintroduction of PSL | Remission‡ |
12 | 17/M | A few months after | CyA | CyA | Remission‡ |
13 | 59/M | 30 years before | Total gastrectomy due to gastric tubular adenocarcinoma | None | ND |
14 | 71/M | 12 months after | PSL and azathioprine (75 mg/day) | CyA and rituximab in addition to azathioprine | Remission§ |
The present case | 47/M | 29 months after | PSL | Pulse methylprednisolone (tapered later) and CyA | Remission |
†Remission was defined as both regression of clinical symptoms of CCS and proteinuria. ‡No endoscopic findings after treatment were described. §In this case, symptoms of CCS improved after additional CyA treatment, whereas his proteinuria did not resolve. Rituximab resulted in a regression of his MN and endoscopic findings. CCS: Cronkhite-Canada Syndrome, MN: membranous nephropathy, CyA: cyclosporine A, PSL: prednisolone, M: male, ND: not described