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. 2020 Nov 12;72(9):475–487. doi: 10.1007/s00251-020-01187-1

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — DNA alignment of two segments of exon 2, with translations in amino acids. Representative alleles of all nonhuman primate species are present. Lowercase letters refer to synonymous differences as compared with the HLA-F*01:01, whereas capitals indicate nonsynonymous changes. The hyphens represent missing nucleotides in comparison to the human reference sequence. The codon for tryptophan in human and orangutan sequences at position 247-249 is shaded. The alignment of the full-length sequences is included as Supplementary Fig. 1