Table 1.
Clinical, serum biochemistry, and cardiac ultrasound parameters.
| Overall (n = 177) | sUA>5.6 mg/dl (n = 51) | sUA ≤5.6 mg/dl (n = 126) | p | |
|---|---|---|---|---|
| Clinical | ||||
| Age, years | 60.3, 13.3 | 60.0, 13.3 | 60.5, 13.3 | 0.71 |
| Men, n (%) | 85 (48.0) | 33 (64.7) | 52 (41.3) | 0.005 |
| BMI, kg/m2 | 28.9, 5.6 | 29.1, 5.3 | 28.8, 5.8 | 0.15 |
| HR, beats/min | 71.5, 12.3 | 72.1, 10.1 | 71.7, 13.2 | 0.51 |
| SBP, mmHg | 144.7, 19.2 | 146.7, 19.9 | 143.9, 18.9 | 0.74 |
| DBP, mmHg | 86.3, 12.1 | 87.1, 13.5 | 85.9, 11.5 | 0.64 |
| Pulse pressure, mmHg | 58.4, 14.1 | 59.6, 14.8 | 57.0, 13.8 | 0.96 |
| ABI | 1.3, 0.2 | 1.2, 0.2 | 1.3, 0.1 | 0.01 |
| Duration of hypertension, years | 8.4, 7.1 | 9.4, 7.8 | 8.0, 6.8 | 0.21 |
| Current-smokers, n (%) | 46 (27.5) | 16 (32.0) | 30 (25.6) | 0.40 |
| Serum biochemistry | ||||
| TC, mg/dl | 193.7, 40.1 | 192.8, 41.2 | 194.0, 39.8 | 0.85 |
| HDL, mg/dl | 54.3, 14.9 | 48.4, 12.4 | 56.7, 15.2 | 0.001 |
| LDL, mg/dl | 114.5, 36.6 | 113.9, 39.7 | 114.7, 35.4 | 0.89 |
| Triglycerides, mg/dl | 124.6, 59.6 | 152.6, 61.2 | 113.3, 55.3 | 0.001 |
| sGlucose, mg/dl | 103.9, 22.00 | 110.9, 27.6 | 101.1, 20.3 | 0.01 |
| sCreatinine, mg/dl | 0.9, 0.2 | 1.0, 0.2 | 0.9, 0.2 | 0.01 |
| sUrea, mg/dl | 40.3, 11.5 | 43.0, 13.4 | 39.2, 10.5 | 0.045 |
| eGFR, ml/min/1.73m2 | 91.9, 33.4 | 88.3, 36.06 | 93.4, 32.3 | 0.36 |
| sUA, mg/dl | 4.99, 1.30 | 6.52, 0.77 | 4.38, 0.88 | 0.001 |
| Cardiac ultrasound | ||||
| LVMi, g/m2.7 | 51.4, 13.8 | 54.7, 15.2 | 49.1, 13.0 | 0.04 |
| LVEF, % | 65.9, 10.1 | 65.8, 11.1 | 66.9, 9.8 | 0.49 |
| RWT, % | 0.4, 0.1 | 0.4, 0.1 | 0.4, 0.1 | 0.57 |
| LAD, mm | 39.1, 5.8 | 39.0, 4.8 | 38.9, 6.2 | 0.56 |
| E/A | 0.9, 0.3 | 0.9, 0.3 | 0.9, 0.3 | 0.96 |
| DT, ms | 204.2, 56.0 | 207.5, 55.0 | 202.4, 56.5 | 0.60 |
| E/E' | 7.4, 2.1 | 6.9, 2.2 | 7.8, 2.0 | 0.15 |
| IVSd, mm | 11.4, 2.1 | 12.3, 2.3 | 11.0, 2.0 | 0.001 |
BMI, body mass index; HR, heart rate; SBP, systolic blood pressure; DBP, diastolic blood pressure; ABI, ankle-brachial index; TC, total cholesterol; HDL, high-density lipoprotein; LDL, low-density lipoprotein; eGFR, estimated glomerular filtration rate; LVMi, left ventricular mass index; LVEF, left ventricular ejection fraction; RWT, relative wall thickness; LAD, left atrial diameter; E, early-wave transmitral diastolic velocity; A, late-wave transmitral diastolic velocity; E', early-diastolic velocity at tissue Doppler imaging; DT, deceleration time; IVSd, diastolic intraventricular septum diameter; sGlucose, serum glucose; sCreatinine, serum creatinine; sUrea, serum urea; sUA, serum uric acid. Data are presented as means ± SD unless otherwise indicated. p-values were calculated by unpaired t-test for continuous variables, or χ2 test for frequencies. Bold values indicate statistical significance (p < 0.05).