Table 4.

The correlation coefficient, rate constant and half-life obtained by fitting the sorafenib release data into the PBS solution at pH 4.8 and pH 7.4.

Sample	pH	Saturation release (%)	R2			Pseudo 2nd order rate constant (k(mg/min)	t½
			Pseudo first order	Pseudo 2nd order	Parabolic Diffusion model
A	4.8	99	0.9901	0.9907	0.8633	2.4 × 10−2	134
B	4.8	98	0.9469	0.9863	0.8552	3.29 × 10−2	150
C	7.4	95	0.9447	0.9502	0.8822	8.63 × 10−5	181
D	7.4	91	0.9009	0.9128	0.8460	7.75 × 10−5	213