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. 2020 Nov 26;11:581691. doi: 10.3389/fphar.2020.581691

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Copyright © 2020 Li, Bai, Xing, Pang, Liu, Liu and Gu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Action mechanism diagram of MXSG. (A) SARS-CoV-2 entry, replication, and PI3K/AKT signaling pathway infected with SARS-CoV-2. The green arrows indicated downregulated genes, and the red arrows indicated upregulated genes with MXSG or its ingredients intervention. The yellow arrows indicated MXSG regulates the intrusion and replication of viruses. The blue arrows indicated MXSG might play antiviral effect in regulating the interaction between PI3K/AKT and virus invasion and replication. (B) Toll-like receptors signaling pathway infected with the severe/mild SARS-CoV-2. The green box indicated downregulated genes with MXSG or its ingredient intervention.