Figure 3.

Cumulative Frequency of the Fold Change in Local F-actin Concentration Relative to the Parent Compartment for Bifurcating (Green), Elongating (Black), and Terminating (Red) Compartments

A value of 0 indicates unchanged F-actin concentration; a value of −1 indicates complete F-actin disappearance (100% decrease relative to parent compartment); and a value of +1 indicates doubling F-actin concentration (100% increase relative to parent compartment). Class I (A), class IV (B), and mutant class IV Form3OE (C) distributions are shown separately. In all three cases, the bifurcating line is clearly right shifted relative to the terminating and elongating lines. The arrowheads in the inset confocal images point to representative branch points. Triple asterisks indicate significantly different comparisons with p < 0.001, Bonferroni-corrected 1-tail t test. See also Figures S5–S9.