Table II. Average EC50 values from JNL dose-response curves.
EC50 values for FcγR2A- and FcγR3A-mediated responses. Average antibody concentrations for half-maximal responses (EC50) and standard deviations of the mean (±) were calculated from at least three independent experiments with each allotype of FcγR2A and FcγR3A in combination with each subclass of human and rhesus IgG (top panels) and Fc domain variants of IgG1 with G236A and DEL substitutions (bottom panels).
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