Figure 5.
Phosphorylated ribosomal S6 (pS6) expression in subregions of the prefrontal cortex and amygdala in male rats exposed to either social rearing (SR) or post-weaning social isolation (PSI), then conditioned social fear procedures. Prelimbic (PL), there were no group differences in pS6 expression. Infralimbic (IL), there was less pS6 expression in Paired rats (both SR and PSI) compared to rats that only received a footshock (* p < 0.05). Ventral Orbital (VO), there was less pS6 expression in Paired rats (both SR and PSI) compared to rats that only received a footshock (* p < 0.05). Basolateral Amygdala (BLA), there was more pS6 expression in Paired rats in the SR group compared to Footshock only rats (* p < 0.05). Central Amygdala (CeA), there were no effects of housing or condition. Medial Ventral Amygdala (MeV), there was more pS6 expression in Paired rats in the PSI group compared to footshock only rats (* p < 0.05).