Table 5.
Paths for serial mediation analyses of the effect of impulsivity/hyperactivity symptoms on inhibition accuracy via the pallidal-thalamic-motor pathway
| GPe/GPi |
Thalamus |
Motor |
Accuracy |
|||||||||||||
| b | SE | P | b | SE | P | b | SE | P | b | SE | P | |||||
| Intercept | b0 | 0.75 | 0.16 | <.001 | b0,1 | 0.26 | 0.18 | <.001 | b0,2 | 1.05 | 0.27 | <.001 | b0,3 | 83.4 | 2.8 | <.001 |
| Impulsivity | a1 | −0.35 | 0.13 | .010 | a2 | −0.12 | 0.14 | .376 | a3 | −0.25 | 0.21 | .238 | c1 | −6.0 | 2.0 | .004 |
| GPe/GPi | d1,2 | 0.67 | 0.10 | .008 | d1,3 | 0.47 | 0.18 | .008 | b1 | −1.8 | 1.8 | .319 | ||||
| Thalamus | d2,3 | 0.37 | 0.14 | .013 | b2 | −0.7 | 1.4 | .618 | ||||||||
| M1 | b3 | 2.7 | 1.0 | .005 | ||||||||||||
| F, R2 | 6.87 | 0.06 | .010 | 26.04 | 0.34 | <.001 | 12.59 | 0.27 | <.001 | 5.01 | 0.17 | .001 | ||||
| Indirect Path | Effect | B. SE | B. CI | |||||||||||||
| Total Indirect Effect | −0.61 | 0.91 | −2.62 | 1.07 | ||||||||||||
| Impulsivity → GPe/GPi → Accuracy | 0.62 | 0.77 | −0.57 | 2.59 | ||||||||||||
| Impulsivity → GPe/GPi → Thalamus → Accuracy | 0.17 | 0.27 | −0.21 | 0.96 | ||||||||||||
| Impulsivity → GPe/GPi → M1 → Accuracy | −0.45 | 0.28 | −1.36 | −0.11 | x | |||||||||||
| Impulsivity → GPe/GPi → Thalamus → M1 → Accuracy | −0.23 | 0.16 | −0.76 | −0.04 | x | |||||||||||
| Impulsivity → Thalamus → Accuracy | 0.09 | 0.20 | −0.10 | 0.89 | ||||||||||||
| Impulsivity → Thalamus → M1 → Accuracy | −0.12 | 0.16 | −0.64 | 0.06 | ||||||||||||
| Impulsivity → M1 → Accuracy | −0.67 | 0.69 | −2.47 | 0.36 | ||||||||||||
Note. x = P<.05; GPe/GPi=Globus Pallidus Pars Externa/Interna; M1=Primary Motor Cortex. t-statistic = b/SE. CI = confidence interval. B.SE = Bootstrapped Standard Error, B. CI = Bootstrapped confidence interval. The a paths are the associations between impulsivity and the mediator variables. The b paths are the associations between the mediator variable and inhibition accuracy. The c’ path is the direct effect of impulsivity on inhibition accuracy. The d path reflects the associations between the serial mediators.