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. 2020 Dec 9;10:21584. doi: 10.1038/s41598-020-78128-1

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Body weights (mean ± SEM) of proton irradiated and control rats. There were no differences in weight at the time of irradiation. Regardless of dose, irradiated rats had decreased body weights (p < 0.0001). The 11 Gy rats had decreased weights at 5 weeks, no difference at 6 weeks, and decreased weights the rest of the testing period compared with controls.. The 14 Gy and 17 Gy rats had decreased weights at week 1 until the end of testing with the exception of week 6 in the 14 Gy rats when there was no difference compared with controls. n = 10/group for sham controls, 11 Gy, and 17 Gy and 8–10 for 14 Gy.