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. 2020 Nov 26;8:617585. doi: 10.3389/fbioe.2020.617585

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Copyright © 2020 Wang, Wang, Zhao, Yan, Huang, Yin, Huang, Chen and Zhu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Application of Mg-IHC to the repair of critical-sized calvarial defects in mice. (A) Schematic illustration of Mg-IHC for calvarial defects in mice. Four weeks after the use of Mg-IHC in mouse calvarial defects. (B) Schematic representation of micro-CT scan reconstruction. (C) Quantitative results of BV/TV. (D) Quantitative results of BMD. (E) Schematic diagram of H&E staining. (F) Schematic diagram of Masson staining. (G) Quantitative results of total neoplastic tissue at the defect site. (H) Quantitative results of mature bone at defect site. *P < 0.05; **P < 0.01; ***P < 0.001.