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. 2020 Nov 26;7:582890. doi: 10.3389/fcvm.2020.582890

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Copyright © 2020 Wang, Xie, Jiang, Wu, Xue, Dong, Fan, Dai, Chen, Li, Chen, Ye, Fang, Choy, Zhao, Dong and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Hispidulin restored mitochondrial oxidative phosphorylation in mice. (A–O) Relative gene expression levels of oxidative phosphorylation complex subunits including Atp5o (A), Atp5f1 (B), Atp5j1 (C), Usmg5 (D), Atp5b (E), Atp2a2 (F), Atp5a (G), Uqucrc2 (H), Uqucrb (I), Sucla2 (J), Ndufa1 (K), Ndufa5 (L), Ndufa3 (M), Ndufa4 (N), and Ndufs1 (O) were determined by qPCR (n = 3–4). Data are expressed as the mean ± SE. Significance of the difference between DMSO+Sham and DMSO+AB or between Hispidulin+Sham and Hispidulin+AB: ^*p < 0.05; significance of the difference between DMSO+Sham and Hispidulin+Sham or between DMSO+AB and Hispidulin+AB: ^#p < 0.05 (n represents the number of independent experiments).