Table 3.
Association between LDL-C burden and the prevalence of asymptomatic ICAS.
| Q1 (−5.07, 1.07) | Q2 (1.08, 2.72) | Q3 (2.72, 4.24) | Q4 (4.24, 57.32) | P for trend | |
|---|---|---|---|---|---|
| Events, n (%) | 106 (9.76%) | 134 (12.33%) | 136 (12.51%) | 204 (18.77%) | |
| Univariate analysis, OR (95% CI) | 1 | 1.30 (0.99–1.70) | 1.32 (1.01–1.73) | 2.14 (1.66–2.75) | <0.01 |
| Model 1, OR (95% CI) | 1 | 1.35 (1.03–1.78) | 1.46 (1.11–1.92) | 2.17 (1.68–2.81) | <0.01 |
| Model 2, OR (95% CI) | 1 | 1.34 (1.01–1.77) | 1.41 (1.07–1.87) | 2.12 (1.63–2.76) | <0.01 |
| Model 3, OR (95% CI) | 1 | 1.33 (1.01–1.76) | 1.41 (1.07–1.87) | 2.12 (1.63–2.76) | <0.01 |
| Model 4, OR (95% CI) | 1 | 1.47 (1.05–2.07) | 1.59 (1.13–2.24) | 2.47 (1.78–3.43) | <0.01 |
| Model 5, OR (95% CI) | 1 | 1.33 (0.96–1.84) | 1.51 (1.09–2.08) | 2.29 (1.68–3.12) | <0.01 |
OR (95% CI): odds ratio (95% confidence interval).
Model 1: adjusted by age and sex on the basis of univariate analysis.
Model 2: adjusted by smoking, drinking, BMI, history of hypertension, diabetes mellitus and hypercholesterolemia, physical activity, income status on the basis of Model 1.
Model 3: adjusted by antihypertensive medication, antidiabetic medication, lipid-lowering medication on the basis of Model 2.
Model 4: excluding subjects with age ≥ 65 y on the basis of Model 3.
Model 5: excluding subjects with a history of hypertensive, diabetes mellitus, hyperlipidemia on the basis of Model 3.