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. 2020 Nov 26;8:600032. doi: 10.3389/fbioe.2020.600032

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Copyright © 2020 Xin, Yuan, Mu, Li, Song and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Surgical procedure diagram in a perforated SM model. (A) Preparation of A-PRF. (B1) Symmetrical bone defects were obtained, and bone plates were acquired correspondingly. (B2) SM was detached and elevated from bony walls (marked with white arrow). Rhythmic movement of SM during respiration (black arrow). (B3) SM was perforated with a 1-cm incision (marked with the white dotted box). (B4) CM or A-PRF was placed onto the perforated SM. (B5) The sinuses were filled with DBBM (marked with black arrows). Finally, the bone defects were covered with bone plates.