Table 2.
Haematological and blood biochemical measurements of the 72 age-matched pairs of pediatric COVID-19 patients and patients with adenovirus respiratory infection
| Characteristics | Adenovirus (N = 72) | COVID-19 (N = 72) | p |
|---|---|---|---|
| Blood routine (n = 58) | |||
| Lymphocyte percentage (IQR) (%) | 41.5(26.8–53.8) | 53.9(40.6–68.9) | < 0.001 |
| Neutrophil count (IQR) (× 109/L) | 3.8(2.1–6.7) | 2.2(1.4–3.9) | 0.004 |
| Neutrophil percentage (IQR) ( × 109/L) | 44.5(35.0–64.3) | 35.3(20.3–48.0) | < 0.001 |
| Hemoglobin (IQR) (g/L) | 111.0(101.8–121.3) | 121.0(113.3–128.5) | < 0.001 |
| Coagulation function (n = 52) | |||
| APTT (IQR) (s) | 43.1(38.1–47.4) | 34.6(30.9–40.1) | < 0.001 |
| PT (IQR) (s) | 13.1(12.5–14.0) | 11.4(10.8–12.7) | < 0.001 |
| Blood biochemistry | |||
| Albumin (IQR) (g/L), n = 64 | 38.0(33.7–41.3) | 44.3(42.1–46.4) | < 0.001 |
| Total bilirubin (IQR) (µmol/L), n = 64 | 3.95(3.02–5.63) | 6.25(4.48–9.48) | < 0.001 |
| LDH (IQR) (U/L), n = 64 | 342.5(273.3–484.0) | 284.5(237.3–366.0) | 0.004 |
| CRP (IQR) (mg/L), n = 60 | 11.7(3.7–40.2) | 0.8(0.8–5.0) | < 0.001 |
| Procalcitonin (IQR) (ng/L), n = 44 | 0.3(0.1–1.3) | 0.1(0.0–0.1) | < 0.001 |
| Potassium (IQR) (mmol/L), n = 67 | 3.8(3.4–4.2) | 4.5(4.1–5.1) | < 0.001 |
| Sodium (IQR) (mmol/L), n = 67 | 135.0(132.0–138.3) | 138.5(137.0–140.0) | < 0.001 |
For each measurement, the exact number of patient pairs included in the analysis varied due to missing values. Distribution of the measurements is denoted by median and interquartile range (in parentheses). The p values were calculated using Wilcoxon signed-rank test
APTT activated partial thromboplastin time, COVID-19 coronavirus disease 19, CRP C-reactive protein, IQR interquartile range, LDH lactate dehydrogenase, PT prothrombin time