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. 2020 Nov 26;10:602089. doi: 10.3389/fcimb.2020.602089

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Copyright © 2020 Martin-Souto, Buldain, Areitio, Aparicio-Fernandez, Antoran, Bouchara, Martin-Gomez, Rementeria, Hernando and Ramirez-Garcia

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Screening of the immunoreactivity of Cystic Fibrosis (CF) patients’ sera against Scedosporium boydii protein extracts. Total WCP (A), Secretome (B), Total CSP (C), and Conidial CSP (D). Specific IgG antibody response is represented for the five sera selected from each group (Scedo+, Asp+ and Scedo-/Asp-) and against each protein extract, by relative Abs value at 450 nm obtained for each serum. Wide horizontal lines depict the media, and short horizontal lines represent the standard deviation (SD). Median value obtained for group Scedo+ is significantly different from that obtained for each of the other two groups, and for the sum of both (as negative samples) (^***p < 0.001; ^**p < 0.01).