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. 2020 Nov 26;11:603931. doi: 10.3389/fmicb.2020.603931

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Copyright © 2020 Drouot, Hantz, Jouen, Velay, Lamia, Veber, Sibilia, Lotellier, Candon, Alain, Fafi-Kremer and Boyer.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Antibody response to SARS-CoV-2 at day > 13 post infection. (A) Anti-S1 IgG (median = 276 AU/mL), (B) Anti-N IgG (median = 1,434 AU/mL), (C) Anti-S1 IgM level (median = 48 AU/mL). Numbers in parenthesis indicate the percentages of data above and below the threshold. (D–F) Receiver Operating Characteristic (ROC) curve of ALBIA-IgG-S1, ALBIA-IgG-N and ALBIA-S1-IgM. The dotted line indicates the threshold value of ‘mean + 3 standard deviations (M + 3SD)’ of the control distribution. D, day post-symptoms. Se: Sensitivity and Sp: specificity.