Table 3.
Correlation of weight gain or weight loss with various neurophysiological parameters in the VP
| Membrane potential | AP frequency | APs/+80 pA step | Minimal latency to first AP (+20 pA step) | eIPSC amplitude (% change after HFS) | sIPSC amplitude | sIPSC frequency (IEI) | IPSC5\IPSC1 (50 HZ) | |
|---|---|---|---|---|---|---|---|---|
| Weight gain | *p = 0.01 r = 0.38 |
p = 0.06 r = −0.31 |
p = 0.56 r = −0.1 |
p = 0.62 r = −0.1 |
*p = 0.04 r = 0.45 |
p = 0.4 r = 0.14 |
p = 0.87 r = 0.03 |
p = 0.17 r = 0.25 |
| Weight loss |
p = 0.54 r = 0.09 |
p = 0.15 r = 0.24 |
p = 0.84 r = 0.03 |
p = 0.88 r = 0.02 |
p = 0.87 r = 0.03 |
p = 0.34 r = 0.15 |
p = 0.31 r = 0.16 |
p = 0.54 r = 0.09 |
r, nonparametric Spearman correlation; weight gain, weight on the last day of HFHS diet expressed as percentage of weight on first day of HFHS diet; weight loss, weight on last day of the 2 weeks of chow following the HFHS diet expressed as percentage of weight on last day of HFHS diet; average weight loss, WG % weight loss (−9.257 ± 4.029% for WG mice; −10.83 ± 2.263% for NWG mice). AP, Action potential. The asterisk highlights the tests where p < 0.05.