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. 2020 Dec 9;134(23):3175–3193. doi: 10.1042/CS20201207

Figure 4. Overexpressed GNMT and treatment with carnosine have a similar cellular protective role.

Figure 4

(A) Real-time PCR of GNMT in MTECs. (B) Western blot of GNMT in MTECs. (C) Western blot of KIM-1 and cleaved caspase-3 in MTECs. (D) Western blot of p65 NF-κB phosphorylation, Col-I and α-SMA in MTECs. Results represent means ± SEM for three independent experiments. *P<0.05, ***P<0.001 vs NC. #P<0.05, ###P<0.001 vs GNMT-OE group. $P<0.05, $$P<0.01, $$$P<0.001 vs HG. Abbreviations: HG, high glucose. CAR, carnosine. EV, empty vector; OE, overexpression.