TABLE 1.
Patient distribution
| No of cases (%) | P‐value | ||||
|---|---|---|---|---|---|
| Modified stage | |||||
| Total | Stage IIIa | Stage IIIb | Stage IIIc | ||
| n = 6855 | n = 3448 | n = 2387 | n = 1020 | ||
| Age a | |||||
| ≤59 y | 2414 | 1219 (50.5) | 798 (33.1) | 397 (16.5) | .0001 |
| 60‐69 y | 2354 | 1237 (52.6) | 791 (33.6) | 326 (13.9) | |
| ≥70 y | 2064 | 976 (47.3) | 792 (38.4) | 296 (14.3) | |
| Sex b | |||||
| Male | 3140 | 1571 (50.0) | 1111 (35.4) | 458 (14.6) | .66 |
| Female | 3703 | 1870 (50.5) | 1274 (34.4) | 559 (15.1) | |
| Tumor location | |||||
| Right‐side | 2058 | 977 (47.5) | 790 (38.4) | 291 (14.1) | <.0001 |
| Left‐side | 1992 | 1097 (55.1) | 683 (34.3) | 212 (10.6) | |
| Rectum | 2805 | 1374 (49.0) | 914 (32.6) | 517 (18.4) | |
| Depth | |||||
| T1 | 150 | 150 (100) | 0 (0) | 0 (0) | <.0001 |
| T2 | 596 | 534 (89.6) | 62 (10.4) | 0 (0) | |
| T3 | 3967 | 2764 (69.7) | 583 (14.7) | 620 (15.6) | |
| T4a | 1782 | 0 (0) | 1503 (84.3) | 279 (15.7) | |
| T4b | 360 | 0 (0) | 239 (66.4) | 121 (33.6) | |
| TNM‐N status | |||||
| N1 | 5020 | 3393 (67.6) | 1421 (28.3) | 206 (4.1) | <.0001 |
| N2a | 1168 | 55 (4.7) | 941 (80.6) | 172 (14.7) | |
| N2b | 667 | 0 (0) | 25 (3.8) | 642 (96.3) | |
| N3 status | |||||
| N3− | 6302 | 3448 (54.7) | 2341 (37.2) | 513 (8.1) | <.0001 |
| N3+ | 553 | 0 (0) | 46 (8.3) | 507 (91.7) | |
| JSCCR(9th)‐N status | |||||
| N1 | 4787 | 3393 (70.9) | 1394 (29.1) | 0 (0) | <.0001 |
| N2a | 1029 | 55 (5.3) | 931 (90.5) | 43 (4.2) | |
| N2b/N3 | 1039 | 0 (0) | 62 (6.0) | 977 (94.0) | |
| TNM‐stage | |||||
| IIIA | 656 | 629 (95.9) | 27 (4.1) | 0 (0) | <.0001 |
| IIIB | 6864 | 2819 (58.0) | 1773 (36.5) | 272 (5.6) | |
| IIIC | 1335 | 0 (0) | 587 (44.0) | 748 (56.0) | |
| JSCCR(9th)‐stage | |||||
| IIIa | 629 | 629 (100) | 0 (0) | 0 (0) | <.0001 |
| IIIb | 4619 | 2819 (61.0) | 1800 (39.0) | 0 (0) | |
| IIIc | 1607 | 0 (0) | 587 (36.5) | 1020 (63.5) | |
| Number of LNs examined c | |||||
| ≤11 | 1590 | 892 (56.1) | 532 (33.5) | 166 (10.4) | <.0001 |
| ≥12 | 4910 | 2367 (48.2) | 1730 (35.2) | 813 (16.6) | |
| Adjuvant‐chemotherapy d | |||||
| Chemotherapy | 1838 | 869 (47.3) | 655 (35.6) | 314 (17.1) | .0023 |
| Surgery alone | 924 | 500 (54.1) | 296 (32.0) | 128 (13.9) | |
Abbreviation: TNM, tumor‐node‐metastasis; JSCCR, Japanese Society for Cancer of the Colon and Rectum.
a
Information of age is not available for 23 patients.
b
Information of sex is not available for 12 patients.
c
Information of number of LNs examined is not available for 355 patients.
d
Information of adjuvant chemotherapy is not available for 4093 patients.