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. 2020 Dec 10;44(1):74–85. doi: 10.1016/j.bj.2020.12.002

Fig. 1.

Fig. 1

The life cycle of SARS-CoV-2, and probable targets of different antiviral drugs being repurposed or investigated for COVID-19. Abbreviations used: ACE2: angiotensin-converting enzyme 2; HCQ: hydroxychloroquine; TMPRSS2: transmembrane protease serine 2; mRNA: messenger RNA; +ssRNA: positive-strand RNA; pp1ab: polyprotein 1 ab; ER: endoplasmic reticulum; ERGIC: ER-Golgi intermediate compartment (Adopted from Saha et al. [12]).