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. 2020 Nov 29;21(12):e51061. doi: 10.15252/embr.202051061

Table 1.

The analysed legislative proposals and their respective main characteristics.

No. Proponent Nature of deregulation Scope of deregulation Formal approval Type of institution
1 Deutsche Akademie der Naturforscher Leopoldina (Leopoldina et al, 2019)

Change in definition: only organisms containing recombinant DNA are GMOs.

Null segregants, products of SDN1 and SDN2 and cisgenesis are not GMO

All organisms Confirmation of status Academic institution
2 Association Française des Biotechnologies Végétales/Wissenschaftlerkreis Grüne Gentechnik e.V. (AFBV & WGG, 2020)

Exclusion of null segregants.

Exemption of products of SDN1 and SDN2, and cisgenesis/intragenesis.

All organisms (but the authors claim that they had plants in mind) Confirmation of status NGO
3 The Government of the Kingdom of Netherlands (The Government of Netherlands, 2017) Exemption of plants being products of SDN1 and SDN2, cisgenesis/intragenesis and null segregants. Plants Justification after the release, at the behest of the European Commission or member state Government
4 Deutsche Akademie der Naturforscher Leopoldina (Leopoldina et al, 2019) Exemption of null segregants, products of SDN1 and SDN2 and cisgenesis. All organisms Confirmation of status Academic institution
5 Grow Scientific Progress (European Citizen’s Initiative, 2019) Exemption of various products based on a pre‐approved list of traits known to exist in the past. Organisms featuring predefined traits Notification procedure Group of students
6 A coalition of Norwegian experts coordinated by the Norwegian Biotechnology Advisory Board (Bratlie et al, 2019) Tiered approach: Exclusion of null segregants; products of genome editing that could be achieved during conventional breeding subject to notification; products of cisgenesis/intragenesis subject to expedited approval. All organisms Depending on nature of the changes Expert body

GMO, genetically modified organism; NGO, non‐governmental organisation; SDN, site‐directed nuclease.