Table 3:

Causes of Death

Causes of death, N (%)	No TMA (n=10644)	TMA (n=429)
Organ failure	1848 (17)	104 (24)
Multisystem organ failure	359	25
Pulmonary failure	413	23
ARDS	228	15
IPS	117	7
Pneumonitis	65	1
DAD or other pulmonary syndrome	23	1
Cardiac failure	220	12
Liver failure	62	3
VOD/SOS	99	4
Renal failure	38	6
CNS failure	37	1
Other organ failure or not specified	187	6
Primary Disease	4738 (45)	96 (22)
Infection	1715 (16)	87 (20)
Graft versus Host disease	1275 (12)	81 (19)
Hemorrhage or vascular	266 (3)	35 (8)
Second malignancy	224 (2)	3 (<1)
Graft rejection/failure	151 (1)	2 (<1)
Other/unknown	427 (4)	21 (5)

Abbreviations: IPS - Idiopathic pulmonary syndrome, DAD – diffuse alveolar damage, ARDS – acute respiratory distress syndrome, VOD – veno-occlusive disease, SOS - sinusoidal obstruction syndrome, CNS – central nervous system