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. 2020 Nov 24;12(3):8867. doi: 10.4081/or.2020.8867

Table 1.

Criteria for PJI.

European Bone Joint Infection Society criteria17 Musculoskeletal Infection Society criteria18
A PJI is diagnosed if at least one of the following criteria is fulfilled:
1) Clinical: sinus tract (fistula) or purulence around prosthesis
2) Cell count in joint aspiration: > 2000/μl leukocytes or >70%
polymorphonuclear granulocytes (PMN)
3) Histology: inflammation in periprosthetic tissue (type 2 or 3
after Krenn and Morawietz)
4) Microbial growth in synovial fluid or ≥ 2 tissue samples
(in cases of high virulent microbes like Staphylococcus aureus
one sample is considered sufficient) or sonication fluid ≥ 50 CFU/ml
Definition of Periprosthetic Join Infection According to the International Consensus Group.
This Is an Adaptation of the Musculoskeletal Infection Society Definition of PJI.
PJI Is Present When One of the Major Criteria Exists or Three Out of Five Minor Criteria Exist
Major Criteria:
Two positive periprosthetic cultures with phenotypically identical organisms, OR
A sinus tract communicating with the joint, OR
Minor Criteria
1) Elevated serum C-reactive protein (CRP) AND erythrocyte sedimentation rate (ESR)
2) Elevated synovial fluid white blood cell (WBC) count OR ++change on leukocyte esterase test stri
3) Elevated synovial fluid polymorphonuclear neutrophil percentage (PMN%)
4) Positive histological analysis of periprosthetic tissue KRENN??
5) A single positive culture

Abbreviations: PJI periprosthetic joint infection.