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. 2020 Dec 9;20:21. doi: 10.1186/s12895-020-00120-z

Table 3.

Laboratory changes from baseline to > six months, categorized according to weight loss status

Parameter Non-successful weight loss patients Successful weight loss patients P. value (mean changes from baseline to > 6 months between weight loss groups)
n Mean changes from baseline to > 6 months (95% CI) p. value n Mean changes from baseline to > 6 months (95% CI) p. value
Hb 14 −0.22 (− 0.83, 0.38) 0.44 33 − 0.35 (− 0.71, 0.004) 0.05 0.69
Plt (×103) 14 −19.29 (− 41.58, 3.006) 0.08 33 −35.12 (−51.61, − 18.63) < 0.001* 0.27
WBC (× 103) 14 − 1.5 (−2.67, − 0.33) 0.02* 33 −2.88 (− 3.68, − 2.09) < 0.001* 0.05
FPG 13 −18.08 (−30.9, − 5.25) 0.01* 29 −7.76 (− 12.97,-2.55) 0.005* 0.07
HbA1C 12 −0.875 (−1.17, − 0.58) < 0.001* 22 − 1.02 (− 1.66,-0.39) 0.003* 0.73
Cr 13 0.04 (−0.07, 0.15) 0.44 33 0.25 (−0.40, 0.90) 0.44 0.68
AST 14 −5.5 (−15.46,4,46) 0.25 33 −7.24 (−14.25, −0.23) 0.04* 0.78
ALT 14 −12.64 (−29.75, 4.47) 0.13 33 −13.39 (−21.91, −4.88) 0.003* 0.93
ALP 5 11.8 (−9.82, 33.42) 0.20 12 6.42 (−6.35, 19.19) 0.29 0.61
TC 9 −2.89 (−49.40, 43.62) 0.89 17 25 (1.71, 48.28) 0.04* 0.20
HDL 9 8 (0.77, 15.23) 0.03* 17 8.23 (3.95,12.52) < 0.001* 0.95
TG 9 −58.22 (− 110.6, −5.84) 0.03* 17 −32.65 (− 54.10, −11.19) 0.005* 0.25
LDL 9 −4.89 (−49.80, 40.02) 0.81 16 11.13 (−10.52, 32.77) 0.29 0.43
Vitamin B12 4 206.48 (− 131.01, 543.96) 0.15 12 − 113.33 (−225.72, −0.93) 0.048* 0.01*
Folate 4 0.52 (−5.38, 6.41) 0.80 12 −2.17 (−5.19, 0.86) 0.14 0.33
Ferritin 3 − 177.3 (− 576.75, 222.15) 0.20 11 1.16 (−59.06, 61.39) 0.97 0.02*
Iron 2 19.5 (− 215.56, 254.56) 0.48 5 −26.2 (−65.32, 12.92) 0.14 0.13
TIBC 1 −22 4 −95.25 (− 121.79, − 68.71) 0.001* 0.03*
Vitamin D 8 10.74 (−3.13, 24.62) 0.11 15 25.67 (−11.03, 62.37) 0.16 0.54

Hb hemoglobin (g/dL), Plt platelet (x103g/dL), WBC White blood cells (x103g/dL), FPG fasting plasma glucose, HbA1C hemoglobinA1C, Cr creatinine, AST Aspartate aminotransferase, ALT Alanine aminotransferase, ALP alkaline phosphatase, TC total cholesterol, HDL high-density lipoprotein, TG triglyceride, LDL low-density lipoprotein, TIBC total iron binding capacity

*p < 0.05